MacuLogix AdaptDx

AdaptDx® functional test enables diagnosis of age-related macular degeneration at its earliest stages. It allows you to proactively treat and monitor the disease in order to slow its progression and preserve vision.

Bring AMD out of the darkness

Subtle, yet progressive, night blindness is the first symptom of AMD. Often presented as problems driving or reading at night, impaired dark adaptation function is the first biomarker of AMD – with  impairment taking place at least three years before drusen are visible. Therefore, assessing how well patients' eyes can adapt from bright light to darkness makes it possible to detect AMD at a subclinical stage.

AdaptDx® is the only test for dark adaptation that can be used in a clinical setting quickly and effectively, using an objective functional measurement called the Rod Intercept™ (RI™). 

AdaptDx Test

  • Highly accurate – dark adaptation testing is 90% accurate in detecting dark adaptation impairment consistent with AMD
  • Easy to interpret – automated, objective, functional measurement

AMD is More Common than You Think

As the leading cause of adult blindness, AMD is three times more prevalent than glaucoma. However, that statistic is probably much higher considering how much disease is being missed. The AMD problem is expected to get much worse as the aging population grows and we live longer lives.

Drusen are Just the Tip of the Iceberg

Studies have found cholesterol accumulates in the retina prior to the formation of drusen. These deposits block nutrient absorption of RPE cells and, as these degenerate, photoreceptor function becomes impaired. This results in problems with dark adadptation – night vision difficulties – the first symptom of AMD.

Subclinical AMD is the Earliest Stage of the Disease

During the subclinical stage of AMD, patients usually have good corrected visual acuity and the retina appears normal upon clinical examination. But while the structure of the macula might appear healthy, there is already an invisible layer of cholesterol deposits that impairs dark adaptation function. 

Dark Adaptation Testing is Highly Specific and Sensitive to AMD

Testing for dark adaptation correctly identifies impairment associated with AMD - and is more accurate than visual field testing for glaucoma.

Detect AMD Three Years Before Drusen are Visible

The AdaptDx® is a simple, fully-automated dark adaptometer that has the power to identify dark adaptation impairment—the earliest warning sign of age-related macular degeneration (AMD).


Interpret Test Results Quickly & Easily

The Rod Intercept™ – RI™– is an objective, automated measure of retinal function that clearly indentifies dark adaptation impairment associated with AMD. 

Monitor AMD Progression

Testing with  AdaptDx at regular intervals allows you to detect changes in dark adaptation impairment associated with progression of AMD, facilitating prompt intervention.


Drive Revenue

Monitor patients more frequently, and derive revenue from auxiliary testing, nutraceutical, and optical sales.

Seamlessly Integrate AdaptDx into Your Practice

AdaptDx®  is the only test for dark adaptation that can be used in a clinical setting quickly and effectively. The AdaptDx Rapid Test takes less than 6.5 minutes to perform.

AdaptDx may find macular degeneration at least three years before you actually see any clinical signs. Do you want to wait to diagnose glaucoma until someone has a vision-threatening visual field loss? No, you don’t. And we should be thinking the same way about AMD. Let’s find it in its earliest stage so that we can do something about it and try to prevent the bad outcomes.

Jeffry Gerson, OD, FAAO, Department of Ophthalmology

University of Kansas School of Medicine

I feel that the AdaptDx instrument from Maculogix is the most significant diagnostic breakthrough in my career! We finally have an instrument that helps us diagnose AMD before vision loss occurs.

Gary Kirman, OD

Kirman Eye

Practical Guidelines for the Treatment of AMD


Practical Perspectives on the Diagnosis Management of AMD


Practical Perspectives on the Diagnosis Management of AMD



MacuLogix AdaptDx Brochure


MacuLogix AdaptDx Testing Protocol


ALSTAR Study – Delayed Dark Adaptation Indicates Subclinical AMD at Least 3 yrs Before Clinically Evident


Diagnostic Sensitivity and Specificity of Dark Adaptation for Detection of AMD


Who Said There's Nothing You Can Do About Early AMD?




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AMD Academy

As an AdaptDx® user you're an important part of our mission to eliminate blindness caused by age-related macular degeneration (AMD).
To help you positively impact your patients' outcomes, MacuLogix has created the AMD Academy™. This is not only a place to view training and learn, but also a growing community. Join the AMD Academy today to start your learning journey, ask questions, find answers, share your successes, and feel supported in your profession.

Visit the Academy