Levulan® Photodynamic Therapy- An Effective Therapeutic Approach to Manage Actinic Keratoses
Levulan® Photodynamic Therapy using the BLU-U® Blue Light Photodynamic Therapy Illuminator is an advanced 2-step treatment for minimally to moderately thick Grade 1 or 2 AKs (AKs that have not yet become enlarged and thick) of the face or scalp. This therapy is unique because it uses a light activated drug therapy to destroy AKs. The 2-step process consists of treatment with Levulan® Kerastick Topical Solution, 20% and the BLU-U® Blue Light Photodynamic Therapy Illuminator (BLU-U®).
Efficacy proven in medical studies
Many of the patients participating in the studies experienced 75-100% clearance of Grade 1 or 2 AKs eight weeks after treatment with Levulan® Kerastick Topical Solution and BLU-U®.
Percent of patients who had a 75-100% response at 8 weeks
At 8 weeks…
• 75% clearance of AK lesions was experienced by 77% of patients treated with Levulan® PDT vs 18% of vehicle-treated patients (p<0.001)
• 83% of the patients treated with Levulan® had 75% clearance of face lesions and 58% of the patients had 75% clearance of scalp lesions.
• 100% clearance of AK lesions was experienced by 66% of patients treated with Levulan® PDT vs 11% of vehicle-treated patients (p<0.001)
• 70% of the patients treated with Levulan® had 100% clearance of face lesions and 53% of the patients had 100% clearance of scalp lesions.
Most patients rated the cosmetic response as good to excellent
Based on the combined results of two medical studies, 94% of patients treated with Levulan® PDT and BLU-U® rated the cosmetic response as good to excellent.
Additionally, no scarring was reported during the medical studies. The most common side effects experienced by patients in these medical studies included scaling/crusting, hypo/hyper-pigmentation, itching, stinging, and/or burning, redness and swelling. Severe stinging and/or burning at one or more lesions being treated was reported by at least 50% of patients at some time during treatment.
